How does the Test Work?

During pregnancy your blood contains cell-free DNA fragments, your own and fetal ones. NIPT is based on 1) extracting cell-free DNA from your blood sample and 2) analyzing the cell-free fetal DNA by modern technology to detect numerical deviations, specifically for the chromosomes 21, 18, 13, X and Y.

During pregnancy cell-free maternal and fetal DNA fragments are in the maternal circulation. They originate from the placenta.

All NIPTs require a sufficient proportion of cell free fetal DNA (cffDNA). Prenatalis® yields reliable results at a cffDNA concentration of approx. 2.7%. Despite this low detection limit, it is currently recommended to wait until the 10th week of pregnancy to take a blood sample.

The analysis usually takes 8-10 business days.