Screened autosomal aneuploidies:
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards Syndrome)
Trisomy 13 (Patau Syndrome)
Screened gonosomal aneuploidies:
45,X (Ullrich-Turner Syndrome)
47,XXX (Triple X Syndrome)
47,XYY (Double Y Syndrome)
47,XXY (Klinefelter Syndrome)
ISO 15189 marked NIPT
The non-invasive prenatal test Prenatalis® is the first NIPT in Germany to meet the standards and guidelines set down by Germany’s National Accreditation Body (DAkkS). DAkkS evaluates the quality and accuracy of products, processes, services and systems. A successful completion of the accreditation process demonstrates the technical and medical competence of the Medical Genetics Laboratory.
Please find more information about the DAkkS here.
NIPT may minimize the need for invasive prenatal diagnostics for questions regarding trisomy 21, 18, 13 and optionally gonosomal aberrations. Positive NIPT results, however, should in any case be confirmed by diagnostic puncture .
Twin and IVF pregnancies
Prenatalis® NIPT is applicable from 10 weeks of gestation for both twin pregnancies and IVF pregnancies.
High sensitivity and specificity
The Prenatalis® test uses Massive Parallel Sequencing based on the Illumina verifi® method, which has been acknowledged to exhibit a particularly high sensivity and specificity of detecting trisomy 21, 18, 13 and X, Y by various studies [2,3,4]).